CHICAGO—Decitabine extends overall survival and improves response rates compared with standard therapies in the treatment of older patients with newly diagnosed acute myelogenous leukemia (AML), said Xavier G. Thomas, MD, PhD.
The treatment options for older patients with AML are limited. Intensive chemotherapy is generally poorly tolerated in this group, the initial mortality rate is high (exceeding 30% at 8 weeks), the response rate to chemotherapy is poor, and relapse rates are high.
CHICAGO—Oncology nurses know that nutrition interventions can help their patients, both during and after active treatment. But the evidence is scant, and personalizing it for each patient can be a challenge. To help, nutrition experts provided useful tips for nurses, along with a discussion of the evidence.
BOSTON—The national discourse on cancer screening has come a long way since 1988, when Ronald Reagan became the first president to say “breast cancer” in public, noted Alec Stone, MA, MPA, Health Policy Director, Oncology Nursing Society (ONS). After the US Preventive Services Task Force (USPSTF) recommended mammography screening every 2 years instead of annually, beginning at 50 years of age instead of 40, the public outcry was widespread and loud. Controversy has also been swirling about prostate cancer screening recommendations.
BOSTON—Treating patients with cancer who are morbidly obese presents unexpected challenges according to Vita Norton, RN, BSN, OCN, and Michelle Howard, RN, BSN, of Mass - achusetts General Hospital in Boston. Data indicate that obesity significantly increases the risk of endometrial and ovarian cancers and is associated with worse outcomes.
BOSTON—Recognizing steroid-induced hyperglycemia early and addressing it promptly can prevent significant ad - verse effects associated with this complication. Educating patients on the importance of and methods for maintaining good blood glucose control helps mitigate damage to the vascular system and kidneys from hyperglycemia. It also lessens susceptibility to infection, a complication of hyperglycemia that is of serious concern in immunocompromised patients. Read More ›
In its update of its technology assessment guidelines on chemotherapy sensitivity and resistance assays (CSRAs), the American Society of Clinical Oncology (ASCO) cautioned against the use of this technology to select chemotherapeutic agents for individual patients. Rather, the guidelines recommend that oncologists “make chemotherapy treatment recommendations based on published reports of clinical trials and a patient's health status and treatment preferences.”
Oncology specialists from around the world gathered in Chicago to hear the latest research in cancer and how these new therapies and strategies will impact patient care. Interestingly, none of the plenary sessions this year focused on the major cancer types, such as breast and lung. Instead the abstracts were chosen because they have the greatest opportunity to change practice, including two presentations in melanoma, one in GIST, and two in pediatric oncology.
Read all of our 2011 ASCO Annual Meeting Coverage
CHICAGO—Women considered at risk for breast cancer developed fewer breast cancers and fewer precursor lesions by taking the aromatase inhibitor (AI) exemestane for 5 years, versus placebo, in a large Canadian study presented at the 2011 annual meeting of the American Society of Clinical Oncology.
CHICAGO—More support for bevacizumab in the treatment of ovarian cancer emerged at the 2011 annual meeting of the American Society of Clinical Oncology, with studies showing the drug prolongs the time to disease progression, both in the metastatic and primary disease settings.
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