Ovarian Cancer

Results of the phase 1b FORWARD II trial show that the MIRV/bevacizumab combination demonstrates promising antitumor activity with durable responses and favorable tolerability in high FRα recurrent ovarian cancer. Read More ›

Results of the NeoPembrOV phase 2 trial support the safe addition of pembrolizumab to neoadjuvant chemotherapy in patients deemed nonoptimally resectable. Although the addition of pembrolizumab resulted in an improved complete resection rate, it did not provide a progression-free survival benefit. Read More ›

Primary results of a randomized phase 3 trial indicate that prolonged treatment with bevacizumab for up to 30 months does not provide survival benefit in patients with advanced ovarian cancer; therefore, bevacizumab treatment duration of 15 months remains the standard of care in this setting. Read More ›

Results of a dose-escalation phase 1 study indicated that AVB-500 is well-tolerated in combination with paclitaxel or pegylated liposomal doxorubicin, with higher antitumor activity seen in combination with paclitaxel, and no previous exposure to bevacizumab. Read More ›

Pooled analysis data from the PRIMA, NOVA, and NORA trials suggest that patients with BRCA-mutated ovarian cancer derive a significant progression-free survival benefit from niraparib maintenance treatment, with no new safety signals. Read More ›

Results of the C-MOnGene study support the adoption of a collaborative oncogenetic model that provides flexible, patient-centered, and efficient genetic counseling and testing for hereditary breast and ovarian cancer and serves as an example for other institutions to incorporate these aspects into their oncology care. Read More ›

Results from a retrospective analysis indicate that health education, using a clinical nursing pathway, results in a more effective understanding of ovarian cancer, reduced psychological burden, improved sleep quality, decreased incidence of complications, improved self-care agency, and improved quality of life among patients with ovarian cancer. Read More ›

The findings of a prospective study suggest that immunologic response to SARS-CoV-2 vaccination is lower among patients with ovarian cancer who are receiving treatment compared with healthy volunteers, indicating that such patients should maintain precautions against COVID-19 despite vaccination. Read More ›

Findings of a retrospective study indicate that patients with platinum-sensitive recurrent ovarian cancer were increasingly being administered maintenance therapy after second-line or third-line platinum-based chemotherapy regardless of biomarker status. Read More ›

This review outlines the disruptions to delivery of cancer care caused by the COVID pandemic, including delays in diagnosis, surgery, and treatment, as well as the psychological impact. Read More ›

Page 3 of 13


Subscribe Today!

To sign up for our newsletter or print publications, please enter your contact information below.

I'd like to receive: