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2021 Year in Review - Gastrointestinal Cancer
Pembrolizumab Monotherapy in Patients with Refractory Esophageal Cancer Conveys Modest Efficacy
2021 Year in Review - Gastrointestinal Cancer
Clinical study results indicate pembrolizumab monotherapy improves response rate in patients with advanced refractory esophageal cancer.
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JAVELIN Gastric 100 Clinical Trial Results Demonstrate No Advantage for Avelumab vs Continued Chemotherapy
2021 Year in Review - Gastrointestinal Cancer
Avelumab maintenance therapy conveys no overall survival difference over the use of continued chemotherapy in patients with advanced GEJC or gastric cancer.
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EMERGE Clinical Trial Phase 2A Domatinostat Dose Escalation
2021 Year in Review - Gastrointestinal Cancer
The dose-escalation phase of the EMERGE clinical trial results show that 200 mg domatinostat twice daily is safe and efficacious.
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PLATFORM Trial Analysis for Durvalumab Demonstrates Patient Subset Gained Radiological Response
2021 Year in Review - Gastrointestinal Cancer
No survival advantage was observed with durvalumab use in the PLATFORM clinical trial, but a patient subgroup was observed to have a radiological response.
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CheckMate-577: Nivolumab Adjuvant Therapy in Patients with Resected Esophageal or GEJ Cancer Is Associated with Significant Disease-Free Survival
2021 Year in Review - Gastrointestinal Cancer
CheckMate-577 clinical trial results show nivolumab adjuvant therapy increases disease-free survival over placebo in patients with gastroesophageal junction (GEJ) cancer or esophageal cancer.
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Retrospective Study of Nivolumab Monotherapy Treatment Lines
2021 Year in Review - Gastrointestinal Cancer
Second-line or later nivolumab monotherapy yields no clear evidence of efficacy advantage for patients with advanced esophageal cancer.
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LEAP-005 Clinical Trial Yields Promising Efficacy and Safety Data for Patients with Gastric Cancer
2021 Year in Review - Gastrointestinal Cancer
Recently released positive findings from the LEAP-005 trial of lenvatinib plus pembrolizumab in the treatment of previously treated gastric cancer leads to cohort expansion.
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CheckMate-648: Nivolumab with Ipilimumab or Chemotherapy Improves OS in Patients with Advanced Esophageal Squamous-Cell Carcinoma
2021 Year in Review - Gastrointestinal Cancer
Results from the CheckMate-648 study demonstrate that nivolumab added to either ipilimumab or chemotherapy improves overall survival in patients with advanced esophageal squamous-cell carcinoma.
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DisTinGuish Part A Trial of DKN-01 plus Tislelizumab and CAPOX Results Indicate Early Activity in Patients with Advanced DKK1-High Gastroesophageal Adenocarcinoma
2021 Year in Review - Gastrointestinal Cancer
DKN-01 plus tislelizumab and CAPOX combination demonstrates promising response rates and safety data in phase 2a study.
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CheckMate-649: Survival Outcome Improved in Patients with Advanced Gastric/Esophageal Cancer Treated with Nivolumab Combined with Chemotherapy
2021 Year in Review - Gastrointestinal Cancer
Nivolumab combined with chemotherapy had improved survival outcomes and an acceptable safety profile in patients with advanced gastric/esophageal cancer, according to CheckMate-649 study results.
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Home
Issues
Online First
2023
August 2023 - Vol 16 No 4
June 2023 - Vol 16 No 3
April 2023 - Vol 16 No 2
February 2023 - Vol 16 No 1
2022
December 2022 - Vol 15 No 6
October 2022 - Vol 15 No 5
August 2022 - Vol 15 No 4
June 2022 - Vol 15 No 3
April 2022 - Vol 15 No 2
February 2022 - Vol 15 No 1
Issue Archive
Special Issues
Supplements
ASK THE EXPERT:
First-Line Treatment of Metastatic Non-Small-Cell Lung Cancer: Checkmate 9LA
Guide to New FDA Approvals
Categories
Conference Correspondent
ONS 2023 - Multiple Myeloma: Wrap-Up
LBCL 2022 - Year in Review
Web Exclusives
Interview with the Innovators
Drug Updates
Media Library
Videos
Rapid Reactions
Audiocasts
Ask the Experts
Master Class Series
Resources
Quick Quiz
CE
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