TON - April 2012, Vol 5, No 3

Q: Is it safe for women at risk for breast cancer–related lymphedema to lift weights?

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Sarah is a 59-year-old female referred by her OB/GYN provider for genetic counseling and cancer risk assessment. She has never had a diagnosis of cancer, colonic polyps, or benign tumors. Additionally, she has never undergone any risk-reducing surgeries, and no family members have undergone genetic testing. When making her appointment, she expresses concern about her risk of pancreatic cancer because 2 of her brothers died of it (per medical records adenocarcinoma of the pancreas). What else would you want to know? 

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Spring is upon us, and with it comes the prospect of new beginnings with flowers blooming and trees, plants, and bushes budding with the fruits and vegetables of the season. The warm breeze of spring brings motivation to start the “spring cleaning” of our diets. There is no better way to shape up a diet than to start incorporating more cruciferous vegetables into the diet.

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The Ohio State University (OSU) Wexner Medical Center, located in Columbus, Ohio, is one of the largest medical centers in the country. As the only academic medical center in central Ohio, it includes the College of Medicine, more than a dozen research centers, and 20 core laboratories, as well as 6 hospitals. 

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The shift from dose-intense standard chemotherapy to therapies targeting specific signaling pathways, molecular targets, or elements of the tumor microenvironment presents a number of challenges to the oncology professional and the patient. Read More ›


According to 2 large breast cancer trials, CYP2D6 genotyping was not predictive of the effectiveness of tamoxifen in postmenopausal women. Thus, the results of these studies are not generalizable to premenopausal women. 

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With this issue, we introduce the 4 finalists for the second annual Oncology Nurse Excellence award. The 4 finalists—Darcie Deaver, MSN, NP-C; Wendy Miano, RN, MSN, DNP, DN; Patricia (Patti) Palmer, RN, MS, AOCN; and Deborah Thompson, BSN, ONC—were selected from among the many nominations we received. Given the caliber of all the nominees, it was very difficult to narrow it down to just 4 finalists. Read More ›


Because skin is the largest organ in the body, is it not surprising that skin cancer is the most common of all cancers. Melanoma, the most deadly skin cancer, is caused by overexposure to ultraviolet radiation. So with spring in the air and summer right around the corner, let us dig deeper into the statistics surrounding this fatal disease. 

Melanoma accounts for about 4% of all skin cancer cases but 79% of all skin cancer deaths. 

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The term “chemo brain” was coined to describe mild cognitive problems in cancer patients attributed to chemotherapy. Although minor chemotherapy-induced memory and cognitive impairments have been described previously, a case-cohort study suggests that these effects can persist more than 20 years posttherapy. 

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