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Biosimilars
US Oncologists’ Perception of the Efficacy, Safety, and Willingness to Prescribe Biosimilar Cancer Therapies
Biosimilars
2020 Year in Review - Biosimilars
The findings of an online, cross-sectional survey indicate oncologists were less likely to prescribe biosimilars if their practice could lose money and control of the drug, despite clinical safety and efficacy between the biosimilar and originator.
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Adherence Patterns Among Patients Using Infliximab Originator and Its Biosimilars
Biosimilars
2020 Year in Review - Biosimilars
Real-world data indicate treatment adherence was highest among patients who had prior infliximab exposure but no prior infliximab biosimilar use.
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Outcomes in Patients with IBS Who Initiate or Switch to the Infliximab Biosimilar Infliximab-dyyb (ONWARD Study)
Biosimilars
2020 Year in Review - Biosimilars
Real-world data from the ONWARD study indicate that patients with inflammatory bowel syndrome (IBS) who initiate or switch to infliximab-dyyb achieve significant improvement of clinical outcomes and quality of life.
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Real-World Comparison of Reference Infliximab versus the Biosimilar Infliximab-abda in Inflammatory Bowel Disease
Biosimilars
2020 Year in Review - Biosimilars
Data from a large, nationwide, observational cohort study demonstrate that switching from reference infliximab to biosimilar infliximab-abda in patients with inflammatory bowel disease was safe and efficacious compared with continuing reference infliximab.
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Efficacy and Safety Equivalence of MYL-1402O and Reference in First-Line Treatment of Patients with Stage IV Nonsquamous NSCLC
Biosimilars
2020 Year in Review - Biosimilars
Confirmatory phase 3 clinical trial results demonstrated equivalence between MYL-1402O and bevacizumab in terms of efficacy, safety, and immunogenicity in the first-line treatment of patients with stage IV metastatic, nonsquamous non–small-cell lung cancer (NSCLC).
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Clinical Similarity of Bevacizumab Biosimilar MB02 to Reference Bevacizumab in Patients with Nonsquamous NSCLC
Biosimilars
2020 Year in Review - Biosimilars
The results of a phase 3 trial demonstrated the clinical equivalence of MB02 with bevacizumab reference product in terms of efficacy, safety, and immunogenicity in patients with stage IIIB/IV nonsquamous non–small-cell lung cancer (NSCLC).
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Demonstration of Efficacy and Safety Equivalence Between Bevacizumab Biosimilar FKB238 and Bevacizumab Reference in Nonsquamous NSCLC
Biosimilars
2020 Year in Review - Biosimilars
Phase 3 trial results demonstrate equivalence between the bevacizumab biosimilar FKB238 and bevacizumab reference in terms of efficacy and safety in patients with advanced/recurrent nonsquamous non–small-cell lung cancer (NSCLC).
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Efficacy and Safety of ABP 798 versus Rituximab: Comparative Clinical Study in Patients with Non-Hodgkin Lymphoma
Biosimilars
2020 Year in Review - Biosimilars
Final analysis data from a confirmatory, randomized phase 3 study demonstrated clinical similarity between rituximab reference and its biosimilar ABP 798 in patients with CD20-positive non-Hodgkin lymphoma in terms of efficacy, safety, and immunogenicity.
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Efficacy and Safety Results of Sandoz Rituximab Biosimilar for the Treatment of Diffuse Large B-Cell Lymphoma
Biosimilars
2020 Year in Review - Biosimilars
Interim analysis results from the prospective, postapproval REFLECT study indicate the Sandoz rituximab biosimilar treatment was associated with safety and efficacy profiles consistent with those previously described for R-CHOP in untreated patients with diffuse large B-cell lymphoma.
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Biosimilar Pegfilgrastim-cbqv Demonstrates Similar Clinical Efficacy to the Pegfilgrastim Reference in a Real-World Setting
Biosimilars
2020 Year in Review - Biosimilars
A proof-of-concept study showed the feasibility of conducting comparative-effectiveness research at scale to promote value-based decision-making in oncology; it also confirmed efficacy equivalence between the biosimilar pegfilgrastim-cbqv and pegfilgrastim reference for the prophylaxis of chemotherapy-induced febrile neutropenia.
Read More ›
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