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Issues
2021 Issues
June 2021 - Vol 14 No 3
TON - June 2021 Vol 14, No 3
From The Editors June 2021
From the Editor
TON - June 2021 Vol 14, No 3
In the June issue of
The Oncology Nurse-APN/PA
(
TON
), we feature a selection of articles aimed at helping our readers stay informed on important issues relevant to nurses, navigators, and advanced practice providers as they care for patients with cancer.
Read More ›
Nationwide Children’s Hospital: Meeting the Unique Needs of AYA Patients with Cancer
Cancer Center Profile
TON - June 2021 Vol 14, No 3
Nationwide Children’s Hospital in Columbus, OH, is one of the largest pediatric hospitals in the United States and is currently ranked as one of the top 10 children’s hospitals in the country by
US News & World Report
’s 2020-2021 “Best Children’s Hospitals Honor Roll” list.
Read More ›
Recent Progress in the Biomarker Landscape for Gastrointestinal Malignancies
By
Nicholas Sarlis, MD, PhD, FACP
Gastrointestinal Cancers
,
Sarlis Says
TON - June 2021 Vol 14, No 3
Gastrointestinal (GI) malignancies account for 26% of the global cancer incidence and 35% of all cancer-related deaths.
Read More ›
Addition of Copanlisib to Rituximab Improves Outcomes in Indolent NHL
By
Patricia Stewart
AACR Highlights
TON - June 2021 Vol 14, No 3
The addition of the
PI3K
inhibitor copanlisib (Aliopa) to rituximab (Rituxan) reduced the risk for disease progression or death by 48% compared with rituximab alone in patients with relapsed indolent non-Hodgkin lymphoma (NHL) in the phase 3 CHRONOS-3 clinical trial.
Read More ›
Maintenance with PARP Inhibitors Extends Survival in Patients with Advanced Ovarian Cancer
By
William King
Ovarian Cancer
TON - June 2021 Vol 14, No 3
Despite improvements in the treatment of advanced ovarian cancer, less than half of newly diagnosed patients survive longer than 5 years, and relapse rates remain high. At the Society of Gynecologic Oncology (SGO) 2021 Virtual Annual Meeting on Women’s Cancer, experts presented updated results from 2 phase 3 clinical trials showing the benefit of the poly (ADP-ribose) polymerase (PARP) inhibitors olaparib (Lynparza) and niraparib (Zejula) as maintenance therapy in women with advanced or recurrent disease.
Read More ›
Noteworthy Numbers: Neutropenia
Noteworthy Numbers
TON - June 2021 Vol 14, No 3
Neutropenia is characterized by low levels of neutrophils, the white blood cells that fight infections. In general, the condition is defined as an absolute neutrophil count (ANC) <1500/μL.
Read More ›
CD73 Inhibitor–Based Combination Therapy Induces Responses in Patients with Metastatic Pancreatic Cancer
By
William King
Pancreatic Cancer
TON - June 2021 Vol 14, No 3
A small-molecule CD73 inhibitor (AB680) induced a 41% overall response rate (ORR) when combined with chemotherapy (with nab-paclitaxel and gemcitabine), plus the novel PD-1 inhibitor zimberelimab, as a first-line treatment for patients with metastatic pancreatic cancer according to results of the dose-escalation portion of the phase 1/1b ARC-8 study.
Read More ›
Selpercatinib Demonstrates Encouraging Activity in a Range of RET Fusion–Positive Solid Tumors
By
Patricia Stewart
AACR Highlights
TON - June 2021 Vol 14, No 3
Selpercatinib (Retevmo) demonstrated antitumor activity in
RET
fusion–positive tumors other than lung cancer and thyroid cancer, according to interim results from the phase 1/2 LIBRETTO-001 clinical trial.
Read More ›
Study Identifies Inherited Pathogenic Germline Variants in Pediatric Neuroblastoma
By
Patricia Stewart
AACR Highlights
TON - June 2021 Vol 14, No 3
Researchers have identified 2 inherited pathogenic genetic variants in patients with pediatric neuroblastoma, according to results from a study presented at the 2021 virtual American Association for Cancer Research annual meeting.
Read More ›
Becoming Pregnant Is Feasible But Less Likely for Breast Cancer Survivors
By
Patricia Stewart
Survivorship
TON - June 2021 Vol 14, No 3
According to results from a large meta-analysis, breast cancer survivors of child-bearing age are less likely than the general population to get pregnant and face greater risk for certain complications, including preterm labor and cesarean section.
Read More ›
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Issue Archive
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Supplements
ASK THE EXPERT:
First-Line Treatment of Metastatic Non-Small-Cell Lung Cancer: Checkmate 9LA
Guide to New FDA Approvals
2021 Year in Review
Multiple Myeloma
Advances in Dual Immunotherapy Cancer Treatments
Ovarian Cancer
HER2-Negative Breast Cancer
Triple-Negative Breast Cancer
Renal-Cell Carcinoma
Biosimilars
Gastrointestinal Cancer
Non–Small-Cell Lung Cancer
Categories
Conference Correspondent
ASCO 2021 - Breast Cancer
ASCO 2020 - Lung Cancer
ASH 2019 Wrap-Up
ASH 2019 MM
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Interview with the Innovators
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