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February 2019 - Vol 12 No 1
TON - February 2019, Vol 12, No 1
From the Editor - TON February 2019
By
Beth Faiman, PhD, APRN-BC, AOCN
From the Editor
TON - February 2019, Vol 12, No 1
The February issue of
The Oncology Nurse-APN/PA (TON)
is packed with important news and insights for today’s oncology nurse. We start off our coverage with a profile of Rutgers Cancer Institute of New Jersey, New Brunswick, which, in collaboration with RWJBarnabas Health, provides patients with cancer many advanced treatment options. This interview is with Renee Kurz, DNP, RN, FNP-BC, AOCNP, Associate Director, Statewide Research, and Patient and Nursing Education, who was excited to discuss the center’s accreditation as a Provider of Continuing Nursing Education by the American Nurses Credentialing Center. Dr Kurz explained how this accreditation has allowed Rutgers Cancer Institute of New Jersey to offer nurses high-quality oncology education to meet certification or licensure requirements. She also discussed how these educational offerings benefit patients (
click here
).
Read More ›
Rutgers Cancer Institute of New Jersey Offers Continuing Education Opportunities for Oncology Nurses
Cancer Center Profile
TON - February 2019, Vol 12, No 1
Rutgers Cancer Institute of New Jersey, New Brunswick, in collaboration with RWJBarnabas Health, offers patients many advanced cancer treatment options, including immunotherapy, precision medicine, preventive services, and education. In 2018, Rutgers Cancer Institute of New Jersey earned accreditation as a Provider of Continuing Nursing Education by the American Nurses Credentialing Center (ANCC), which recognizes high-quality continuing nursing education, interprofessional continuing education, transition to practice programs, and skills-based competency programs.
Read More ›
5 mg Tamoxifen as Effective as 20 mg Daily in Early Localized Breast Cancer
By
Phoebe Starr
Breast Cancer
TON - February 2019, Vol 12, No 1
The large, randomized TAM-01 clinical trial demonstrated that 5 mg daily of tamoxifen for 3 years halved the risk for recurrence of breast intraepithelial neoplasia—atypical ductal hyperplasia, ductal carcinoma in situ (DCIS), and lobular carcinoma in situ—in women after surgery and reduced the risk for new contralateral breast cancer by 75% compared with placebo.
Read More ›
Weight-Loss Intervention in Women with Breast Cancer Works Only with Adherence
By
Phoebe Starr
Breast Cancer
TON - February 2019, Vol 12, No 1
San Antonio, TX—An interim analysis of a randomized clinical trial showed that a lifestyle intervention aimed at weight loss achieved approximately a 1-kg weight loss in patients with early breast cancer who received chemotherapy, whereas patients in the control group gained approximately 1 kg over the course of the study.
Read More ›
Addressing Financial Toxicity Through Systematic Change
By
Meg Barbor, MPH
Best Practices
TON - February 2019, Vol 12, No 1
Although the cost of care can have severe effects on patients with cancer and their families, oncologists rarely address financial toxicity, according to Hanna K. Sanoff, MD, MPH, Medical Director, University of North Carolina (UNC) NC Cancer Hospital Clinics.
Read More ›
Nivolumab-Ipilimumab Combination Highly Active in Metastatic MSI-H or dMMR Colorectal Cancer
By
Wayne Kuznar
Colorectal Cancer
TON - February 2019, Vol 12, No 1
Munich, Germany—The combination of immunotherapy with nivolumab (Opdivo) and ipilimumab (Yervoy) may soon represent a new first-line treatment option in patients with early-stage metastatic colorectal cancer (CRC) associated with microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) tumors. Two studies presented at the ESMO 2018 Congress demonstrated the efficacy of this combination in this patient population.
Read More ›
Checkpoint Inhibitor a New Approach to Jump-Start a Waning Response to CAR T-Cell Therapy
By
Phoebe Starr
Immunotherapy
TON - February 2019, Vol 12, No 1
Although chimeric antigen receptor (CAR) T-cell therapy has achieved remarkable long-lasting remissions in B-cell malignancies, in approximately 60%, the initial response wanes over time because of “immune exhaustion.”
Read More ›
Paradigm Shift: Radiation a New Standard in Prostate Cancer with Low Metastatic Burden
By
Phoebe Starr
Prostate Cancer
TON - February 2019, Vol 12, No 1
Munich, Germany—For patients with newly diagnosed metastatic prostate cancer, current standard management is androgen-deprivation therapy plus docetaxel (Taxotere). Contrary to previous assumptions, radiation to the primary tumor improves survival in men with low metastatic disease burden. This new finding came from the preplanned analysis of the multiarm, multistage STAMPEDE study presented at the ESMO 2018 Congress by lead investigator Chris C. Parker, MD, FRCR, MRCP, Consultant Clinical Oncologist, Royal Marsden NHS Foundation Trust, Sutton, England. The study was simultaneously published online in
Lancet
.
1
Read More ›
Researchers Identify First Mutation to Explain Resistance to Venetoclax
By
Phoebe Starr
Leukemia
TON - February 2019, Vol 12, No 1
San Diego, CA—The
BCL2
Gly101Val mutation is the first genomic alteration to be identified as responsible for resistance to venetoclax (Venclexta), a potent and effective medication indicated for the treatment of chronic lymphocytic leukemia (CLL). The
BCL2 Gly101Val
mutation is unique to CLL and so far has not been described in other cancers.
Read More ›
First-Line Ibrutinib Improves Outcomes Compared with Current Standard of Care in Older Patients with Chronic Lymphocytic Leukemia
By
Wayne Kuznar
Leukemia
TON - February 2019, Vol 12, No 1
San Diego, CA—Front-line ibrutinib (Imbruvica) therapy results in a lower rate of disease progression or death than the current standard-of-care chemoimmunotherapy with bendamustine (Bendeka) and rituximab (Rituxan) in older patients with chronic lymphocytic leukemia (CLL). Adding rituximab to ibrutinib did not improve outcomes compared with ibrutinib alone, reported Jennifer A. Woyach, MD, Associate Professor, Ohio State University Comprehensive Cancer Center, Columbus, at ASH 2018.
Read More ›
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April 2023 - Vol 16 No 2
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Issue Archive
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Supplements
ASK THE EXPERT:
First-Line Treatment of Metastatic Non-Small-Cell Lung Cancer: Checkmate 9LA
Guide to New FDA Approvals
2021 Year in Review
Multiple Myeloma
Advances in Dual Immunotherapy Cancer Treatments
Ovarian Cancer
HER2-Negative Breast Cancer
Triple-Negative Breast Cancer
Renal-Cell Carcinoma
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Non–Small-Cell Lung Cancer
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Conference Correspondent
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ASH 2019 MM
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CE
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